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On-Going Studies

Automated Contingency Management System for Reduction of Alcohol Use

National Institute on Alcohol Abuse and Alcoholism (NIAAA)
The primary goal of this work is to develop and beta test a mobile app designed to track and manage progress through a heavy drinking protocol that includes contingency management as its primary treatment modality along with biochemical validation through serial submission of breath samples.

Genetic and Environmental Influences on the Relationships Between Smoking and Cannabis Co-Use and Smoking and Alcohol Co-Use and their Association with Chronic Pain: A Twin Study

WSU Alcohol and Drug Abuse Research Program

This study will explore the genetic and environmental influences of co-use of alcohol and cigarettes in the context of the Washington State Twin Registry.

An Addictions Neuroclinical Assessment Based Treatment for Smokers with an Alcohol Use Disorder

National Cancer Institute (NCI)

Our aim is to investigate the combined implementation of two highly promising treatments for comorbid alcohol and nicotine addiction – contingency management and varenicline – as a high-intensity intervention to treat drinking and smoking simultaneously.

Zonisamide for the Treatment of Alcohol Use Disorder in the Addiction Neuroclinical Assessment Framework

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Our aim is to investigate zonisamide as a novel therapy for the treatment of alcohol use disorder using objectively verified urinary abstinence with EtG cups among patients with an alcohol use disorder who will also receive standard, bibliotherapy treatment.

Collaborative Pain Care for Rural Veterans with Substance Use Disorders

Veteran’s Administration (VA)

This program will yield a manualized pain treatment program that can be delivered to rural Veterans receiving VHA care across the U.S. through the VA Office of Rural Health Rural Promising Practices program or other implementation mechanism. As part of this overall project, an implementation tool kit will be developed to aid future VHA sites that wish to adopt this collaborative pain program within their health care systems and medical centers.

Effective Caregiving for Neonatal Abstinence Syndrome: Development of an Instructional Mobile Technology Platform for High-Risk Pregnant Women

National Institute on Drug Abuse (NIDA)

Due to an alarming rise in opioid use among the general population that is mirrored in pregnant women, Neonatal Abstinence Syndrome (NAS) rates have increased in the US from 2004 to 2014. To address this critical gap, this project proposes to adapt an existing mobile NAS tool for clinician training and decision support, for high-risk pregnant women and assess its usability, acceptability, and feasibility in a small randomized controlled analog trial.

Clinical Trials Network: Pacific Northwest Node

National Institute on Drug Abuse (NIDA)

The major goal of this project is to conduct studies of the therapeutic effect of behavioral, pharmacological and combined/integrated treatment interventions in rigorous, multi-site clinical trials to determine the effectiveness across a broad range of community-based treatment settings and diversified populations, and to ensure the transfer of research results to physicians, clinicians, providers, policy makers, and patients.

A Randomized Clinical Analog Trial of Banking Rewards for Decreased Alcohol Consumption

WSU Alcohol and Drug Abuse Research Program

The major goal of this project is to test whether contingency management (CM) in a banking approach will reduce alcohol use.

Connected Pharmacy Platform to Improve Adherence to New Buprenorphine-Naloxone Prescription Treatment of Opioid Use Disorder

National Institute on Drug Abuse (NIDA)

This Fast Track proposal is designed to test, modify, and refine a novel medication adherence tool designed specifically for individuals receiving buprenorphine/naloxone. This represents a unique relationship between an emerging small business and Washington State University.

Chronic Pain Management and Patient-Centered Outcomes Following Discontinuation of Long-Term Opioid Therapy

Veteran’s Administration (VA)

The objective of this study is to characterize patient experiences with the opioid discontinuation process and examine acute, intermediate, and long-term changes in quality of life following discontinuation of long-term opioid therapy.

Neonatal Abstinence Syndrome (NAS) Primer, Reference and Decision Support Tool

National Institute on Drug Abuse (NIDA)

The primary goal of this work is to develop and beta test a mobile assessment tool of neonatal abstinence syndrome among hospital providers.

Integrating Genomic Risk Assessment for Chronic Disease Management in a Diverse Population

National Human Genome Research Institute (NHGRI)

In the United States, 60% of adults have at least one chronic disease such as heart disease, cancer, and diabetes and 40% have two or more. Although research has identified genomic signatures of common diseases, these genomic risk assessments are not used in clinical care to identify, and if appropriate, pre-treat patients at high risk for developing disease. The project aims to establish methods to implement genomic risk assessment and management in clinical care is the vital first step to leverage the power of genomics to prevent disease.