{"id":124,"date":"2022-05-30T08:51:00","date_gmt":"2022-05-30T15:51:00","guid":{"rendered":"https:\/\/labs.wsu.edu\/duttke\/?p=124"},"modified":"2023-04-27T15:32:15","modified_gmt":"2023-04-27T22:32:15","slug":"do-you-want-to-know-more-about-gene-regulation-in-addiction","status":"publish","type":"post","link":"https:\/\/labs.wsu.edu\/duttke\/2022\/05\/30\/do-you-want-to-know-more-about-gene-regulation-in-addiction\/","title":{"rendered":"Do you want to know more about gene regulation in addiction?"},"content":{"rendered":"\n<p>In collaboration with the Telese and Benner labs at UC San Diego we used csRNA-seq to capture changes in brain gene expression in rats with addiction-like behavior and control which identified transcription factor-centered regulatory mechanisms implicated in addiction, including those regulated by glucocorticoid receptors in glial cells. And even cooler, no rats had to die for these experiments as csRNA-seq made is possible to capture the complete transcriptome including unstable enhancer RNAs from banked tissues! (Link to paper: doi: 10.3389\/fnins.2022.858427)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In collaboration with the Telese and Benner labs at UC San Diego we used csRNA-seq to capture changes in brain gene expression in rats with addiction-like behavior and control which identified transcription factor-centered regulatory mechanisms implicated in addiction, including those regulated by glucocorticoid receptors in glial cells. And even cooler, no rats had to die [&hellip;]<\/p>\n","protected":false},"author":33745,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[10],"tags":[],"wsuwp_university_location":[],"wsuwp_university_org":[],"_links":{"self":[{"href":"https:\/\/labs.wsu.edu\/duttke\/wp-json\/wp\/v2\/posts\/124"}],"collection":[{"href":"https:\/\/labs.wsu.edu\/duttke\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/labs.wsu.edu\/duttke\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/labs.wsu.edu\/duttke\/wp-json\/wp\/v2\/users\/33745"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.wsu.edu\/duttke\/wp-json\/wp\/v2\/comments?post=124"}],"version-history":[{"count":1,"href":"https:\/\/labs.wsu.edu\/duttke\/wp-json\/wp\/v2\/posts\/124\/revisions"}],"predecessor-version":[{"id":125,"href":"https:\/\/labs.wsu.edu\/duttke\/wp-json\/wp\/v2\/posts\/124\/revisions\/125"}],"wp:attachment":[{"href":"https:\/\/labs.wsu.edu\/duttke\/wp-json\/wp\/v2\/media?parent=124"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/labs.wsu.edu\/duttke\/wp-json\/wp\/v2\/categories?post=124"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/labs.wsu.edu\/duttke\/wp-json\/wp\/v2\/tags?post=124"},{"taxonomy":"wsuwp_university_location","embeddable":true,"href":"https:\/\/labs.wsu.edu\/duttke\/wp-json\/wp\/v2\/wsuwp_university_location?post=124"},{"taxonomy":"wsuwp_university_org","embeddable":true,"href":"https:\/\/labs.wsu.edu\/duttke\/wp-json\/wp\/v2\/wsuwp_university_org?post=124"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}