The Tasmanian devil (Sarcophilus harrisii) is found only on the environmentally heterogeneous island of Tasmania and is threatened with extinction by a transmissible cancer, devil facial tumor disease (DFTD). In this study, Fraik and colleagues used landscape genomics analyses to investigate the relative effects of abiotic environment versus an infectious cancer (DFTD) on Tasmanian devil populations Several post‐DFTD candidate loci were associated with disease prevalence and were in linkage disequilibrium with genes involved in tumor suppression and immune response. Loss of apparent signal of abiotic local adaptation post‐disease suggests swamping by strong selection resulting from the rapid onset of DFTD. Read the full paper here.