{"id":29,"date":"2018-02-13T14:30:21","date_gmt":"2018-02-13T22:30:21","guid":{"rendered":"http:\/\/labs.wsu.edu\/inlab\/?page_id=29"},"modified":"2024-04-17T07:49:47","modified_gmt":"2024-04-17T14:49:47","slug":"research","status":"publish","type":"page","link":"https:\/\/labs.wsu.edu\/inlab\/research\/","title":{"rendered":"Research"},"content":{"rendered":"<div class=\"breadcrumbs\" typeof=\"BreadcrumbList\" vocab=\"https:\/\/schema.org\/\">\r\n\t<!-- Breadcrumb NavXT 7.2.0 -->\n<span property=\"itemListElement\" typeof=\"ListItem\"><a property=\"item\" typeof=\"WebPage\" title=\"Go to Labs Network Sites.\" href=\"https:\/\/medicine.wsu.edu\/\" class=\"main-home\" ><span property=\"name\">College of Medicine<\/span><\/a><meta property=\"position\" content=\"1\"><\/span> &gt; <span property=\"itemListElement\" typeof=\"ListItem\"><a property=\"item\" typeof=\"WebPage\" title=\"Go to Integrative Brain Function and Neurodevelopment Lab.\" href=\"https:\/\/labs.wsu.edu\/inlab\" class=\"home\" aria-current=\"page\"><span property=\"name\">Integrative Brain Function and Neurodevelopment Lab<\/span><\/a><meta property=\"position\" content=\"2\"><\/span><\/div><header class=\"wsu-article-header \">\r\n\t<h1 class=\"wsu-article-header__title\">\r\n\t\tResearch\t<\/h1>\r\n\t\t<\/header>\r\n\n\n\n<figure class=\"wp-block-embed is-type-rich is-provider-embed-handler wp-block-embed-embed-handler wp-embed-aspect-4-3 wp-has-aspect-ratio wsu-video--width-full\"><div class=\"wp-block-embed__wrapper\">\n<div class='embed-youtube' style='text-align:center; display: block;'><iframe class='youtube-player' type='text\/html' width='640' height='390' src='https:\/\/www.youtube.com\/embed\/UU9c-MhXPZI?version=3&#038;rel=1&#038;fs=1&#038;autohide=2&#038;showsearch=0&#038;showinfo=1&#038;iv_load_policy=1&#038;wmode=transparent' frameborder='0' allowfullscreen='true'><\/iframe><\/div>\n<\/div><\/figure>\n\n\n\n<h2 class=\"wsu-spacing-before--medium wp-block-heading\">Research Projects<\/h2>\n\n\n\n<p><a href=\"https:\/\/news.wsu.edu\/2015\/10\/14\/routine-eye-exam-could-help-detect-autism\/\">Pupil Biomarker Research<\/a> Highlighted Work Conducted at WSU<\/p>\n\n\n\n<hr class=\"wp-block-separator\" \/>\n\n\n\n<h2 class=\"wp-block-heading\">Publications<\/h2>\n\n\n\n<p><strong>Lynch, G.<\/strong>,&nbsp;James, S.M., Cardon, T.A., &amp; McPherson, S.M. (2022). Sensitivity and specificity of pupillary light reflex measures for ASD using monocular pupillometry.&nbsp;<a href=\"https:\/\/link.springer.com\/article\/10.1007\/s10072-022-05976-2\">Neurological Sciences<\/a>,&nbsp;<\/p>\n\n\n\n<p><strong>Lynch, G.<\/strong> (2018). Using pupillometry to assess the atypical pupillary light reflex and LC-NE system in ASD.&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30469373\">Behavioral Sciences, 8<\/a>, 11.&nbsp;<\/p>\n\n\n\n<p><strong>Lynch, G.<\/strong> T. F., James, S., &amp; VanDam, M. (2018). Pupillary response and pheynotype in ASD: Latency to constriction discriminates ASD from typically developing adolescents.&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29087041\">Autism Research<\/a>. <\/p>\n\n\n\n<p>Hseih, M., <strong>Lynch, G.<\/strong> Madison, C. (2018). Intervention techniques used with autism spectrum disorders by speech-language pathologists in the United States and Taiwan: A descriptive analysis of practice in clinical settings. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29710283\">American Journal of Speech-Language Pathology, 27<\/a>. <\/p>\n\n\n\n<p><strong>Lynch, G<\/strong>. (2016). AAC for individuals with autism spectrum disorder: assessment and establishing treatment goals. In Cardon, T. Autism &amp; Child Psychopathology: Technology and Treatment of Children with Autism Spectrum Disorders. Zurich, Switzerland: Springer.<\/p>\n\n\n\n<hr class=\"wp-block-separator\" \/>\n\n\n\n<h2 class=\"wp-block-heading\">Selected Presentations<\/h2>\n\n\n\n<p>Elsisi, Z., Hansen, R., Canestaro, W., &amp; <strong>Lynch, G.<\/strong> (2023 May). <em>Supporting the value of a novel health technology tool to support diagnosis of autism spectrum disorder.<\/em> Poster presentation. Annual meeting of the International Society for Pharmoeconomics and Outcomes, Boston, MA.<\/p>\n\n\n\n<p>Jenson, D.,<strong> Lynch, G.<\/strong>, &amp; James, S.&nbsp;(2022 November). <em>Using EEG and pupillometry to assess cortical and subcortical sensorimotor dynamics: proof of concept.<\/em>&nbsp; Poster presentation, Annual Convention of the American Speech-Language Hearing Association, New Orleans, LA.<\/p>\n\n\n\n<p>Jenson, D., <strong>Lynch, G.<\/strong>, &amp; James, S.&nbsp; (2022 November). <em>Preliminary data quantifying cortical and subcortical contributions to audiovisual speech perception in stuttering and autism.<\/em> Poster presentation, Annual Convention of the American Speech-Language Hearing Association, New Orleans, LA.<\/p>\n\n\n\n<p>Choe, J., Brown, N., Khuu, T., Janout, K., &amp; <strong>Lynch, G.<\/strong> (2022 March). <em>Proof of concept: pupillometry and tropicamide to characterize cholinergic contributions to the PLR in ASD. <\/em>Poster presentation, WSU Health Sciences Inland Northwest Research Symposium, Spokane, WA.<\/p>\n\n\n\n<p><strong>Lynch, G<\/strong>. (2022 July). The pupillary light reflex in ASD: Sensitivity and specificity in children 6-17 years using hand-held monocular pupillometry. Paper presented at <em>7thAnnual Neurological Disorders Summit, NDS 2022, San Francisco, CA.<\/em><\/p>\n\n\n\n<p>Neuenschwander, L.**, Buckley, S., Sidell, D., Morales, K., Brundage, G., Vargas, O.**, Minjarez, M., &amp; <strong>Lynch, G<\/strong>. (2022 May). Output metrics for prototype and reference standard hand-held pupillometers: comparison of pupillary measures for ASD and typical development in children 2-4 years. Poster presentation,&nbsp;<em>Annual Meeting of the International Society for Autism Research,&nbsp;<\/em>Austin, TX.<\/p>\n\n\n\n<p>Bredy, A*., Dechert, C., Simpson, K., and <strong>Lynch, G<\/strong>. (2021 November). Collaborative practices between speech-language pathologists and board-certified behavior analyst serving children with autism spectrum disorder (ASD) in Washington State. Poster presentation. <em>Annual Convention of the American Speech-Language Hearing Association, Washington D.C.<\/em><\/p>\n\n\n\n<p><strong>Lynch, G.<\/strong>, T. Cardon, T A., James, S.M., McPherson, S.M. (2020). <em>Preliminary findings: hand-held pupillometry to detect an atypical PLR threshold in ASD. International Society for Autism Research Annual Meeting, INSAR 2020 Virtual, Seattle, Washington.<\/em><\/p>\n\n\n\n<p><strong>Lynch, G. <\/strong>(2019, July). A Framework for Integrating Service Provision by BCBAs &amp; SLPs Under the ABA Benefit. State-wide presentation funded under the <em>AS3D Grant, Washington State Health Care Authority and Seattle Children\u2019s Hospital<\/em>.<\/p>\n\n\n\n<p><strong>Lynch, G. <\/strong>(2019, March). The Visual Pathway in ASD: Explicit Teaching Methods to Promote Social Communication. <em>Seattle Children\u2019s Hospital Autism Center,<\/em> <em>Seattle, WA. <\/em><\/p>\n\n\n\n<p><strong>Lynch, G.<\/strong> (2018, November). Translating eye-tracking and cognitive demand in ASD: social language stimuli and targeting non-verbal pragmatics.&nbsp;<em>American Speech-Language Hearing Association Annual Convention,<\/em>&nbsp;Boston: MA.<\/p>\n\n\n\n<p><strong>Lynch, G.<\/strong> (2018, November). AAC &amp; ASD: Why use of AAC technology often fails\u2014a guide to evaluation and establishing initial treatment goals.&nbsp;<em>American Speech-Language Hearing Association Annual Convention,<\/em>&nbsp;Boston: MA<\/p>\n\n\n\n<p><strong>Lynch, G.<\/strong> (2018, October). Pupillary reflex in autism spectrum disorders: promise of the neurological exam to support future screening using hand-held technology. <em>Translational Medicine Symposium, Washington State University Health Sciences, Spokane: WA.<\/em><\/p>\n\n\n\n<p><strong>Lynch, G.<\/strong>*, James, S., &amp; VanDam, M. (2018, August). Pupillometry as a method for examining phenotype in ASD: latency to constriction discriminates ASD from typically developing adolescents.&nbsp;<a href=\"http:\/\/jneuroscience.com\/jnen\/articles\/v4n1\/jnen-18-s1-nds.pdf\">Proceedings of the 4th Neurological Disorders Summit (NDS-2018). J Neurol Exp Neurosci 4<\/a> (Suppl 1): (p.28).&nbsp;<\/p>\n\n\n\n<p><strong>Lynch, G.<\/strong>, James, S., Hyslop, R, &amp; VanDam, M. (2017). Preliminary findings in adolescents with ASD: Pupil diameter as a proxy for cognitive load during passive viewing of facial expression stimuli. Poster presentation:&nbsp;<em>Annual Meeting of the International Society of Autism Research,&nbsp;<\/em>San Francisco, CA.<\/p>\n\n\n<div class=\"wsu-row wsu-row--halves\" >\r\n    \n<div class=\"wsu-column\"  style=\"\">\r\n\t\n\n<figure class=\"wp-block-image size-large is-resized\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/s3.wp.wsu.edu\/uploads\/sites\/3419\/2024\/04\/Lars-Dr-Coury-INSAR-2022-792x1114.jpg\" alt=\"Lars Neuenschwander speaking at a Presentation\" class=\"wp-image-430\" width=\"340\" height=\"478\" srcset=\"https:\/\/wpcdn.web.wsu.edu\/wp-labs\/uploads\/sites\/3419\/2024\/04\/Lars-Dr-Coury-INSAR-2022-792x1114.jpg 792w, https:\/\/wpcdn.web.wsu.edu\/wp-labs\/uploads\/sites\/3419\/2024\/04\/Lars-Dr-Coury-INSAR-2022-396x557.jpg 396w, https:\/\/wpcdn.web.wsu.edu\/wp-labs\/uploads\/sites\/3419\/2024\/04\/Lars-Dr-Coury-INSAR-2022-768x1080.jpg 768w, https:\/\/wpcdn.web.wsu.edu\/wp-labs\/uploads\/sites\/3419\/2024\/04\/Lars-Dr-Coury-INSAR-2022-1092x1536.jpg 1092w, https:\/\/wpcdn.web.wsu.edu\/wp-labs\/uploads\/sites\/3419\/2024\/04\/Lars-Dr-Coury-INSAR-2022.jpg 1134w\" sizes=\"(max-width: 340px) 100vw, 340px\" \/><figcaption><em>Lars Neuenschwander at the International Society for Autism Research, Austin, TX, presenting to Daniel Coury, MD, Nationwide Children\u2019s Hospital, Director, Autism Treatment Network<\/em><\/figcaption><\/figure>\n\n<\/div>\r\n\n\n<div class=\"wsu-column\"  style=\"\">\r\n\t\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" loading=\"lazy\" width=\"792\" height=\"386\" src=\"https:\/\/s3.wp.wsu.edu\/uploads\/sites\/3419\/2024\/04\/Kim-Poster-Defense-792x386.jpg\" alt=\"Kimberly Wronkiewicz &amp; Dr. Lynch standing in front of a presentation board\" class=\"wp-image-442\" srcset=\"https:\/\/wpcdn.web.wsu.edu\/wp-labs\/uploads\/sites\/3419\/2024\/04\/Kim-Poster-Defense-792x386.jpg 792w, https:\/\/wpcdn.web.wsu.edu\/wp-labs\/uploads\/sites\/3419\/2024\/04\/Kim-Poster-Defense-396x193.jpg 396w, https:\/\/wpcdn.web.wsu.edu\/wp-labs\/uploads\/sites\/3419\/2024\/04\/Kim-Poster-Defense-768x374.jpg 768w, https:\/\/wpcdn.web.wsu.edu\/wp-labs\/uploads\/sites\/3419\/2024\/04\/Kim-Poster-Defense.jpg 1029w\" sizes=\"(max-width: 792px) 100vw, 792px\" \/><figcaption><em>Kimberly Wronkiewicz (\u201922) &amp; Dr. Lynch<\/em><\/figcaption><\/figure>\n\n<\/div>\r\n\n<\/div>\n\n\n<hr class=\"wp-block-separator\" \/>\n\n\n\n<h2 class=\"wp-block-heading\">Grants<\/h2>\n\n\n\n<h3 class=\"wsu-font-size--xxmedium wp-block-heading\">Washington Research Foundation Phase II Technology Commercialization Award 2022<\/h3>\n\n\n\n<p>PI: Lynch, Co-I: McPherson, S. &nbsp;\u201cValidity and feasibility of pupillometry technology to improve screening for autism spectrum disorder\u201d<\/p>\n\n\n\n<h3 class=\"wsu-font-size--xxmedium wp-block-heading\">The Arc Trust Fund of Washington State, 2021, Lynch (PI)<\/h3>\n\n\n\n<p>\u201cTraining &amp; Intervention Outcomes Using Visual Teaching Methods to Target Nonverbal Communication in Young People with ASD\u201d<\/p>\n\n\n\n<h3 class=\"wsu-font-size--xxmedium wp-block-heading\">Washington Research Foundation 2020, Lynch (PI), McPherson (Co-I) <\/h3>\n\n\n\n<p>&#8220;PLR Biometrics &amp; Hand-held Technology for Non-Invasive ASD Screening&#8221;<br>This grant provides funding for a project aimed at helping health care providers identify autism spectrum disorder (ASD) early during routine healthcare visits. The study involves development of handheld technology that will use measurements of the pupillary light reflex as a noninvasive way to screen for ASD. The new tool will support pediatric medical teams in screening for ASD and help children with ASD access early intervention.<\/p>\n\n\n\n<h3 class=\"wsu-font-size--xxmedium wp-block-heading\">WSU Commercialization Gap Fund 2019, Lynch (PI), Neuenschwander (Co-I)<\/h3>\n\n\n\n<p>\u201cA Novel Approach to Non-invasive Pupillometry Screening for ASD\u201d<br>Sponsored in partnership with Washington Research Foundation, this externally reviewed grant provides support for development of software using PLR biometrics in an integrated tool which will lead to the transfer of science and technology to the private sector. The goal is to develop technology which will support screening for ASD using the PLR biomarker.<\/p>\n\n\n\n<h3 class=\"wsu-font-size--xxmedium wp-block-heading\">WSU Spokane Faculty Seed Grant 2013-2014 (PI)<\/h3>\n\n\n\n<p>\u201cPupil response as a potential screening biomarker in ASD\u201d<\/p>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Research Projects Pupil Biomarker Research Highlighted Work Conducted at WSU Publications Lynch, G.,&nbsp;James, S.M., Cardon, T.A., &amp; McPherson, S.M. (2022). Sensitivity and specificity of pupillary light reflex measures for ASD using monocular pupillometry.&nbsp;Neurological Sciences,&nbsp; Lynch, G. (2018). Using pupillometry to assess the atypical pupillary light reflex and LC-NE system in ASD.&nbsp;Behavioral Sciences, 8, 11.&nbsp; Lynch, [&hellip;]<\/p>\n","protected":false},"author":528,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_wsuwp_accessibility_report":null},"categories":[],"tags":[],"wsuwp_university_location":[],"wsuwp_university_org":[],"_links":{"self":[{"href":"https:\/\/labs.wsu.edu\/inlab\/wp-json\/wp\/v2\/pages\/29"}],"collection":[{"href":"https:\/\/labs.wsu.edu\/inlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.wsu.edu\/inlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.wsu.edu\/inlab\/wp-json\/wp\/v2\/users\/528"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.wsu.edu\/inlab\/wp-json\/wp\/v2\/comments?post=29"}],"version-history":[{"count":50,"href":"https:\/\/labs.wsu.edu\/inlab\/wp-json\/wp\/v2\/pages\/29\/revisions"}],"predecessor-version":[{"id":447,"href":"https:\/\/labs.wsu.edu\/inlab\/wp-json\/wp\/v2\/pages\/29\/revisions\/447"}],"wp:attachment":[{"href":"https:\/\/labs.wsu.edu\/inlab\/wp-json\/wp\/v2\/media?parent=29"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/labs.wsu.edu\/inlab\/wp-json\/wp\/v2\/categories?post=29"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/labs.wsu.edu\/inlab\/wp-json\/wp\/v2\/tags?post=29"},{"taxonomy":"wsuwp_university_location","embeddable":true,"href":"https:\/\/labs.wsu.edu\/inlab\/wp-json\/wp\/v2\/wsuwp_university_location?post=29"},{"taxonomy":"wsuwp_university_org","embeddable":true,"href":"https:\/\/labs.wsu.edu\/inlab\/wp-json\/wp\/v2\/wsuwp_university_org?post=29"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}