Current Projects
Pharmacogenomic Testing to Optimize Opioid Use Disorder Treatment: Acceptability and Feasibility Trial
National Institute of Health (NIH) and National Institute on Drug Abuse (NIDA)
The objective of this study is to develop educational materials on pharmacogenomics relative to opioid use disorder treatment and complete an acceptability and feasibility trial of pharmacogenomics in opioid use disorder treatment.
Off Target Effects of Varenicline and Contingency Management in Multi-Substance Users; Effects on cannabis use in smokers with alcohol use disorder
WSU Alcohol and Drug Abuse Research Program (ADARP)
The objective of this study is to determine whether participants’ biochemically verified cannabis use and cannabis cravings decrease as a result of varenicline administration, as well as qualitatively examine participant perspectives of their motivations for use of cannabis, changes in cannabis use, and relationships within multi-substance use of alcohol, tobacco, and cannabis among individuals. Additionally, this study aims to explore whether cannabis use motives moderate relationships between treatment and cannabis use outcomes.
Cocaine Craving and Use Outcomes Secondary Analysis of a Randomized Study to Test the Safety and Effectiveness of Buprenorphine in the Presence of Naltrexone for the Treatment of Cocaine Dependence
National Institute of Health (NIH) and National Institute on Drug Abuse (NIDA)
This is a supplement to the Clinical Trials Network (CTN) for a secondary data analysis of CTN 0048, “A randomized study to test the safety and effectiveness of buprenorphine in the presence of naltrexone for the treatment of cocaine dependence.” The primary goal of this investigation is to examine the relationships between cocaine craving and multiple substance use outcomes while accounting for heterogeneity in both craven and use patterns over time.
A Phase 2 Clinical Trial on Psilocybin for for Co-Occuring PTSD and Alcohol Use Disorder
Washington State
This is a placebo-controlled, randomized clinical trial funded by the state of Washington to explore the safety and tolerability of psilocybin, paired with psychotherapy to treat Veterans and First Responders with both PTSD and AUD. While there is increasing interest in psilocybin and other psychedelics for individual pathologies, there is a growing need to explore the effects of psilocybin on co-occurring disorders.
This project is in collaboration with the University of Washington’s Center for Novel Therapeutics in Addiction Psychiatry (NTAP)
Clinical Trials Network: Pacific Northwest Node
National Institute of Health (NIH) and National Institute on Drug Abuse (NIDA)
The goal of this project is to conduct studies of the therapeutic effect of behavioral, pharmacological, and combined/integrated treatment interventions in rigorous, multi-site clinical trials to determine the effectiveness across a broad range of community-based treatment settings and diversified populations, and to ensure the transfer of research results to physicians, clinicians, providers, policy makers, and patients.
Past Projects
Exploring Clinical Profile and Treatment Outcome Differences Based on Baseline Smoking and Alcohol Co-Use Status Among Individuals Initiating Medication for Opioid Use Disorder Treatment.
National Cancer Institute and National Drug Abuse Treatment Clinical Trials Network
This study investigates the differences in clinical profiles and treatment outcomes based on smoking and AUD status among individuals initiating MOUD.
Impact of recent stimulant use on treatment outcomes amongst individuals initiating medications for opioid use disorders: Secondary analysis of a multisite randomized controlled trial
Washington State University
This study examines the potential predictive role of stimulant urinalysis result at baseline on treatment retention and opioid and stimulant use outcomes amongst individuals initiating MOUD treatment.
American Indian women’s perceptions of perinatal cannabis use
WSU Alcohol and Drug Abuse Research Program (ADARP)
This study looked to describe perceptions of risks and benefits of perinatal cannabis use in a sample of American Indian perinatal women who report regularly using cannabis while pregnant.
Collaborative Tele-Pain Care for Rural Patients: Results of a Single-Arm Open-Label Pilot Trial
VHA Office of Rural Health
This study aimed to pilot test a collaborative care intervention delivered over telehealth to rural patients engaged with SUD treatment who experienced chronic pain.
Key contextual factors involved with participation in medical and genomic screening and research for African American and White Americans: a qualitative inquiry
National Human Genome Research Institute (NHGRI)
This study aimed to identify key factors to establishing trust in medical and genomic screening and research among African Americans and White Americans.
Understanding Psychedelic-Assisted-Psychotherapy Providers’ Perspective and Insights: A Qualitative Analysis
Washington State University
This study examined underground psychedelic-assisted psychotherapy providers’ protocols and perspectives, to better inform policy and public health, as psychedelics increasingly are used in the United States.
Intervention diversity predicts social rehabilitation indicators at discharge in therapeutic communities
This study analyzed real-world data from the monitoring system implemented in the largest network of institutions receiving public funds in the State of Sao Paulo. Data came from 8109 records of individuals admitted between 2014 and 2016 in 48 institutions.
15-year Survivorship of a Unique Dual-Modular Femoral Stem in Primary Hip Arthroplasty
Washington State University
The objective of this study was to assess the survivorship of a unique dual-modular femoral stem at an average 15-year follow-up period.
Mobile Medication Adherence Platform for Buprenorphine (MAP4BUP): A Pilot Feasibility, Usability and Efficacy Pilot Randomized Clinical Trial
Washington State University
Poor medication adherence is one of the main barriers to the long-term efficacy of buprenorphine/naloxone (BUP/NAL). The aims of this pilot investigation were to examine if a Bluetooth-enabled pill cap and mobile application is a feasible, usable tool for increasing BUP/NAL adherence among people with an opioid use disorder.
Exploring the mediating role of baseline urinalysis results on demographic characteristics and stimulant use disorder treatment outcomes
NIDA
This study aimed to explore the potential mediating role of baseline stimulant UA results on the relationship between baseline characteristics and total number of stimulant negative UAs submitted during treatment.
Patient Feedback on a Mobile Medication Adherence App for Buprenorphine and Naloxone: Closed and Open-Ended Survey on Feasibility and Acceptability
NIDA
This study aimed to examine patient feedback on current and potential features of a Bluetooth-enabled pill bottle cap and associated mobile app for patients prescribed BUP and NAL for an opioid use disorder, and to solicit recommendations for improvement to effectively and appropriately tailor the technology for people in treatment for opioid use disorder.