Taylor presented her study at the ABRCMS and received an award!
She attended the ABRCMS in San Antonio, TX, as a MARC-WSU student and received an award in the developmental biology category!
Congratulations, Taylor!
Taylor received 2nd place at the CVM Research Symposium 2025!
Congratulations, Taylor!
She received 2nd place in the Undergraduate poster competition!!
The screening of “Belowhttps://labs.wsu.edu/hayashi/wp-admin/post.php?post=130&action=edit# The Belt” on October 16, 2025
I am pleased to announce our first outreach program at WSU Pullman. We will host our inaugural event on October 16 at CUE419, from 5-7 pm, featuring the screening of “Below The Belt,” a documentary film about endometriosis, followed by a discussion on the topic, including menstruation, pain, and reproductive health.
Please see the attached flyer and watch the trailer! This documentary film, supported by figures such as Hillary Clinton and Senator Elizabeth Warren, raises awareness about the debilitating disease endometriosis, and has been screened at many Universities.
https://www.belowthebelt.film/
You can invite anyone who would like to join the event! It is Free!
The second screening will be held at WSU Spokane on October 30 at 6-8 pm.
If you have any questions, please do not hesitate to contact Kanako Hayashi (k.hayashi@wsu.edu).
Michael D. Griswold Symposium on Reproductive Health 2025
New Publications!
Shi M, MacLean II JA, Hayashi K. The involvement of peritoneal GATA6+ macrophages in the pathogenesis of endometriosis. Front Immunol 2024. PMID: 39192982 PMCID: PMC11348394.
https://doi.org/10.3389/fimmu.2024.1396000
Zhao L, Shi M, Winuthayanon S, MacLean II JA, Law N, Hayashi K. Environmentally-relevant doses of bisphenol A and S exposure in utero disrupt germ cell programming across generations resolved by single nucleus multi-omics. Environmental Health Perspectives 2025, PMID: 40460421
https://doi.org/10.1289/EHP16981
Shi M, Oh Y, Mitchell DA, MacLean II JA, McLaughlin RJ, Hayashi K. Transgenerational effects of perinatal cannabis exposure on female reproductive parameters in mice. Tox Sci 2025. PMID: 40156136
https://doi.org/10.1093/toxsci/kfaf043
– Selected for the cover page ToxSci June 2025
New Publication!
Herup-Wheeler T, Shi M, Harvey ME, Talwar C, Kommagani R, MacLean JA, Hayashi K. High-fat diets promote peritoneal inflammation and augment endometriosis-associated abdominal hyperalgesia. Front Endocrinol 2024;15:1336496 PMID: 38559689 PMCID: PMC10978581
NWRSS in Bend 2024
Congratulations!
Congratulations Tristin!! He successfully defended his M.S. dissertation today!
A NEW PAPER PUBLISHED in ”COMMUNICATIONS BIOLOGY”
Niclosamide targets the dynamic progression of macrophages for the resolution of endometriosis in a mouse model
Liang’s paper has been published! Congrats, Liang!!
Liang Zhao, a postdoctoral fellow, has reported the heterogeneity of peritoneal macrophages and molecular mechanisms regulating their dynamic progression after lesion induction in a mouse model of endometriosis using scRNA-seq. The study further showed that niclosamide finely reversed those transcriptomic changes of macrophages caused by lesion induction through its stepwise regulations on the differentiation of recruited macrophages, the maturation of transitory LPMs, and the preservation of embryo-derived resident LPMs.
Check our website for your favorite genes!
https://kanakohayashilab.org/hayashi/en/mouse/peritoneal.immune.cells/
The Journal Club: Cannabis & Male Reproductive Function
Discussion around the effects of tetrahydrocannabinol (THC) on sperm function and motility in subsequent generations of mice
SSR in Spokane, 2022
Ming, Liang, Jenna, Aubrey, Constance, and Tristin presented at the SSR on July 26-29, 2022. Ming received 2nd place in the post-doctoral oral competition! Congrats, Ming!
Cougar Cage Award
Our new project, “Nanomedicine systems for the targeted drug delivery in endometriosis therapy” collaborating with Dr. Yuehe Lin receives the Cougar Cage Award!
ADARP fellowship
Good news! Olivia Witherspoon received the ADARP fellowship in the 2022-2023 academic year.
She has also received the TMP undergraduate research scholarship award. Congratulations, Olivia!
NWRSS at Skamania Lodge on May 19-21, 2022
Ming, Liang, Maho, Jenna and Tristin presented at NWRSS on May 19-21, 2022. All did a good job! It was also a cool place to visit!
Check this out!
A New Review Article Published in Cells
Progesterone Actions and Resistance in Gynecological Disorders
- PMID: 35203298
- PMCID: PMC8870180
- DOI: 10.3390/cells11040647
Instagram: @toxspotlight
Our Cannabis study was selected for the cover of the February issue of Toxicological Sciences
INHALED CANNABIS IMPAIRS SPERM
Our first cannabis study has been published in the ToxSci and highlighted in MedicalResearch.com.
The study has received further attention! Please see the release on EurekAlert and WSU Insider!
CRB retreat
We attended the Annual CRB Retreat, on September 30 – October 1, 2021
Ming and Maho received the best poster presentation awards. Congrats, Ming and Maho!!
Our new cannabis study
Our new cannabis study is available here. The results indicate that cannabis vapor exposure generationally affects male reproductive functions, probably due to disruption of spermatogenesis in the developing testis.
