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Research Projects

Pupil Biomarker Research Highlighted Work Conducted at WSU


Lynch, G., James, S.M., Cardon, T.A., & McPherson, S.M. (2022). Sensitivity and specificity of pupillary light reflex measures for ASD using monocular pupillometry. Neurological Sciences

Lynch, G. (2018). Using pupillometry to assess the atypical pupillary light reflex and LC-NE system in ASD. Behavioral Sciences, 8, 11.

Lynch, G. T. F., James, S., & VanDam, M. (2018). Pupillary response and pheynotype in ASD: Latency to constriction discriminates ASD from typically developing adolescents. Autism Research. doi: 10.1002/aur.1888.

Hseih, M., Lynch, G. Madison, C. (2018). Intervention techniques used with autism spectrum disorders by speech-language pathologists in the United States and Taiwan: A descriptive analysis of practice in clinical settings. American Journal of Speech-Language Pathology, 27,.

Lynch, G. (2016). AAC for individuals with autism spectrum disorder: assessment and establishing treatment goals. In Cardon, T. Autism & Child Psychopathology: Technology and Treatment of Children with Autism Spectrum Disorders. Zurich, Switzerland: Springer.


Lynch, G. (2022 July). The pupillary light reflex in ASD: Sensitivity and specificity in children 6-17 years using hand-held monocular pupillometry. Paper presented at 7thAnnual Neurological Disorders Summit, NDS 2022, San Francisco, CA.

Neuenschwander, L.**, Buckley, S., Sidell, D., Morales, K., Brundage, G., Vargas, O.**, Minjarez, M., & Lynch, G. (2022 May). Output metrics for prototype and reference standard hand-held pupillometers: comparison of pupillary measures for ASD and typical development in children 2-4 years. Poster presentation, Annual Meeting of the International Society for Autism Research, Austin, TX.

Bredy, A*., Dechert, C., Simpson, K., and Lynch, G. (2021 November). Collaborative practices between speech-language pathologists and board-certified behavior analyst serving children with autism spectrum disorder (ASD) in Washington State. Poster presentation. Annual Convention of the American Speech-Language Hearing Association, Washington D.C.

Lynch, G., T. Cardon, T A., James, S.M., McPherson, S.M. (2020). Preliminary findings: hand-held pupillometry to detect an atypical PLR threshold in ASD. International Society for Autism Research Annual Meeting, INSAR 2020 Virtual, Seattle, Washington.

Lynch, G. (2019, July). A Framework for Integrating Service Provision by BCBAs & SLPs Under the ABA Benefit. State-wide presentation funded under the AS3D Grant, Washington State Health Care Authority and Seattle Children’s Hospital.

Lynch, G. (2019, March). The Visual Pathway in ASD: Explicit Teaching Methods to Promote Social Communication. Seattle Children’s Hospital Autism Center, Seattle, WA.

Lynch, G. (2018, November). Translating eye-tracking and cognitive demand in ASD: social language stimuli and targeting non-verbal pragmatics. American Speech-Language Hearing Association Annual Convention, Boston: MA.

Lynch, G. (2018, November). AAC & ASD: Why use of AAC technology often fails—a guide to evaluation and establishing initial treatment goals. American Speech-Language Hearing Association Annual Convention, Boston: MA

Lynch, G. (2018, October). Pupillary reflex in autism spectrum disorders: promise of the neurological exam to support future screening using hand-held technology. Translational Medicine Symposium, Washington State University Health Sciences, Spokane: WA.

Lynch, G.*, James, S., & VanDam, M. (2018, August). Pupillometry as a method for examining phenotype in ASD: latency to constriction discriminates ASD from typically developing adolescents. Proceedings of the 4th Neurological Disorders Summit (NDS-2018). J Neurol Exp Neurosci 4 (Suppl 1): (p.28). doi: 10.17756/jnen.2018-suppl1.

Lynch, G., James, S., Hyslop, R, & VanDam, M. (2017). Preliminary findings in adolescents with ASD: Pupil diameter as a proxy for cognitive load during passive viewing of facial expression stimuli. Poster presentation: Annual Meeting of the International Society of Autism Research, San Francisco, CA.

Hseih, Ming-Yeh*, Madison, C., & Lynch, G. (2016, November).  Intervention techniques used with autism spectrum disorders by speech-language pathologists in the United States and in Taiwan: a comparative study. Poster presentation: American Speech-Language Hearing Association (ASHA) Annual Convention, Philadelphia, PA.

Lynch, G., James, S.M., VanDam, M., & Potter, N.L. (2015, May). Facial response to visual stimuli:  using pupil response as an indicator of phenotype in ASD.  Poster presentation: Annual Meeting of the International Society of Autism Research (IMFAR), Salt Lake City, UT.

Davenny, A.*, Lynch, G., & Fuller, D. (2014, November). A survey of parental concerns regarding language skills in young people with ASD. Poster presentation:  American Speech-Language Hearing Association (ASHA) Annual Convention, Orlando, FL.


The Arc Trust Fund of Washington State, 2021, Lynch (PI)
“Training & Intervention Outcomes Using Visual Teaching Methods to Target Nonverbal Communication in Young People with ASD”

Washington Research Foundation 2020, Lynch (PI), McPherson (Co-I)
“PLR Biometrics & Hand-held Technology for Non-Invasive ASD Screening”
This grant provides funding for a project aimed at helping health care providers identify autism spectrum disorder (ASD) early during routine healthcare visits. The study involves development of handheld technology that will use measurements of the pupillary light reflex as a noninvasive way to screen for ASD. The new tool will support pediatric medical teams in screening for ASD and help children with ASD access early intervention.

WSU Commercialization Gap Fund 2019, Lynch (PI), Neuenschwander (Co-I)
“A Novel Approach to Non-invasive Pupillometry Screening for ASD”
Sponsored in partnership with Washington Research Foundation, this externally reviewed grant provides support for development of software using PLR biometrics in an integrated tool which will lead to the transfer of science and technology to the private sector. The goal is to develop technology which will support screening for ASD using the PLR biomarker.

WSU Spokane Faculty Seed Grant 2013-2014 (PI)
“Pupil response as a potential screening biomarker in ASD”