Past five years
Morteza Sarparast, Elham Pourmand, Jennifer Hinman, Derek Vonarx, Tommy Reason, Fan Zhang, Shreya Paithankar, Bin Chen, Babak Borhan, Jennifer L Watts, Jamie Alan, Kin Sing Stephen Lee (2023) “Dihydroxy-Metabolites of Dihomo-γ-linolenic Acid Drive Ferroptosis-Mediated Neurodegeneration” ACS Cent. Sci. 9, 5, 870–882 https://doi.org/10.1021/acscentsci.3c00052
Michael S. Mortensen, Jimena Ruiz, Jennifer L. Watts (2023) “Polyunsaturated Fatty Acids Drive Lipid Peroxidation during Ferroptosis”. Cells 12(5), 804; https://doi.org/10.3390/cells12050804
Marcos A. Perez, Andrea J. Clostio, Isabel R. Houston, Jimena Ruiz, Leslie Magtanong, Scott J. Dixon, Jennifer L. Watts (2022) “Ether lipid deficiency disrupts lipid homeostasis leading to ferroptosis sensitivity”. PLoS Genetics (https://doi.org/10/1371/journal.pgen.1010436. Sept. 30, 2022.
Henry F. Harrison and Jennifer L. Watts (2021) “Lipid Extraction and Analysis” chapter in C. elegans Methods and Applications. 3rd edition. Methods in Molecular Biology, Springer Nature, New York. DOI: 10.1007/978-1-0716-2180-6_14.
Megan Conlon,Carson Poltorack, Giovanni C. Forcina, Alex Wells, Melodie Mallais, Marcos A. Perez, Alexi Kahanu, Leslie Magtanong, Jennifer L. Watts, Derek A. Pratt, Scott J. Dixon (2021) “A Compendium of Kinetic Cell Death Modulatory Profiles Identifies Ferroptosis Regulators.” Nat. Cell Biology 17, 665-675.
Marcos A. Perez and Jennifer L. Watts (2021) “Worms, fat, and death: Caenorhabditis elegans lipid metabolites regulate cell death” Metabolites 2021, 11, 125.
Jason S Watts, Henry F Harrison, Shizue Omi, Quentin Guenthers, James Dalelio, Nathalie Pujol, Jennifer L Watts (2020). “New Strains for tissue-specific RNAi studies in Caenorhabditis elegans”. G3 vol 10(11) 4167-4176.
Manish Chamoli, Anita Goyala, Syed Tabrez, Atif Siddiqui, Anupama Singh, Gordon Lithgow, Jennifer Watts, and Arnab Mukhopadhyay (2020) “Polyunsaturated fatty acids and p38 MAPK pathway links metabolic reprogramming to cytoprotective gene expression during Dietary Restriction” Nature Communications 11(1) 1-13.
Marcos A. Perez, Leslie Magtanong, Scott J. Dixon, Jennifer L. Watts (2020). “Dietary Induction and Modulation of Ferroptosis in Caenorhabditis elegans” Developmental Cell 54(4) 417-454.
Anubhuti Dixit, Anjali Sandhu, Souvik Modi, Meghana Shashikanth, Sandhya P. Koushika, Jennifer L. Watts, and Varsha Singh (2020). “Neuronal control of lipid metabolism by STR-2 GPCR promotes longevity in C. elegans” Aging Cell 19(6) 313160.
Andrea J. Connor and Jennifer L. Watts (2019) “Omega-3 and Omega-6 fatty acid metabolism: Modeling growth and disease using Caenorhabditis elegans”, pp 107-116. Omega Fatty Acids in Brain and Neurological Health, 2nd edition.Ronald R. Watson and Victor R. Preedy, ed., 2019. Book Chapter. ISBN: 978-0-12-815238-6
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Jason Watts, Diane Morton, Kenneth J. Kemphues, Jennifer L. Watts (2018). “The biotin-ligating protein BPL-1 is critical for lipid biosynthesis and polarization of the Caenorhabditis elegans embryo” Journal of Biological Chemistry 293(2): 610-622.
Jennifer L. Watts and Michael Ristow (2017) “Lipid and Carbohydrate Metabolism in Caenorhabditis elegans”. Genetics (Wormbook) 2017, 207(2), 413-466.
Xun Shi, Pablo Tarazona, Trisha J. Brock, John Browse, Ivo Feussner, Jennifer L. Watts (2016). “A C. elegans model for ether lipid biosynthesis and function” Journal of Lipid Research 57(2): 265-75.
Jennifer L. Watts (2016) “Using Caenorhabditis elegans to Uncover Conserved Functions of Omega-3 and Omega-6 Fatty Acids” J. Clin. Med. 2016, 5(2), 19.
Marshall Deline, Julia Keller, Michael Rothe, Wolf-Hagen Schunck, Ralph Menzel, Jennifer L. Watts (2015). “Epoxides Derived from Dietary Dihomo-Gamma-Linolenic Acid Induce Germ Cell Death in C. elegans” Scientific Reports 5:15417 | DOI: 10.1038/srep15417.
Wei Ding, Lorissa J. Smulan, Nicole S. Hou, StefanTaubert, Jennifer L. Watts, Amy K. Walker (2015) “s-Adenosylmethionine Levels Govern Innate Immunity through Distinct Methylation-Dependent Pathways” Cell Metabolism 2015 Aug 22: 1-22.
Tracy L. Vrablik, Vladislav A. Putyuk, Emily M. Larson, Richard D. Smith, Jennifer L. Watts (2015), “Lipidomic and proteomic analysis of Caenorhabditis elegans lipid droplets and identification of ACS-4 as a lipid droplet-associated protein” BBA – Molecular and Cellular Biology of Lipids 1851 (10) 1337-1345.
Nicole S. Hou, Daniel Y. Choi, Keouna Pather, Aljona Gutschmidt, Xun Shi, Jennifer L. Watts, Thorsten Hoppe and Stefan Taubert (2014), “Activation of the endoplasmic reticulum unfolded protein response by lipid disequilibrium without disturbed proteostasis in vivo.” Proc. Nat. Acad. Sci. USA 111 (22) E2271-E2280.
Xun Shi, Juan Li, Xiaoju Zou, Joel Greggain, Seven V. Rodkaer, Nils J. Faergeman, Bin Liang, and Jennifer L. Watts (2013), “The regulation of lipid droplet size and phospholipid composition by stearoyl-CoA desaturase”, Journal of Lipid Research 54(9):2504-14.
Yen-Lin Chu, Xiling Wu, Jing Xu, Jennifer L. Watts, Chengtao Her (2013) “DNA damage induced MutS homologue hMSH4 acetylation”, International Journal of Molecular Sciences 14(10):20966-82.
Christopher M. Webster, Marshall Deline, Jennifer L. Watts (2013), “Stress response pathways confer protection from omega-6 polyunsaturated fatty acid-mediated destruction of germ cells in C. elegans”, Developmental Biology 373(1):14-25.
Jennifer L. Watts (2013) “Physiological Functions and Regulation of C. elegans Stearoyl-CoA Desaturases”, pp 195-207. Stearoyl-CoA Desaturase Genes in Lipid Metabolism, Ed. James M. Ntambi. Book Chapter. ISBN: 978-1-4614-7968-0
Tracy L. Vrablik and Jennifer L. Watts (2013) “Polyunsaturated Fatty Acid Derived Signaling in Reproduction and Development: Insights from C. elegans and Drosophila”, Molecular Reproduction and Development 80(4) 244-59. Review.
Tracy L. Vrablik and Jennifer L. Watts (2012) “Emerging Roles for Specific Fatty Acids in Developmental Processes”. Genes and Development 26(7) 631-7. Perspective.
Maria A. Lim, Mary A. Selak, Zhongmin Xiang, Dimitri Krainc, Rachael L. Neve, Brian C. Kraemer, Jennifer L. Watts, and Robert G. Kalb (2012) “Reduced Activity of AMP-Activated Protein Kinase (AMPK) Protects against Genetic Models of Motor Neuron Disease” Journal of Neuroscience 18:32(3): 1123-1141.
*Amy K. Walker, Rene L. Jacobs, Jennifer L. Watts, Veerle Rottiers, Karen Jiang, Deirdre M. Finnegan, Toshi Shioda, Malene Hansen, Fajun Yang, Lorissa J. Niebergall, Dennis E. Vance, Monika Tzoneva, Anne C. Hart and Anders M. Naar (2011) “A Conserved SREBP-1/Phosphatidylcholine Feedback Circuit Regulates Lipogenesis in Metazoans”. Cell 147(4): 840-852.
*Bargavi Thyagarajan, Adam G. Blaszczak, Jennifer L. Watts, W. Evan Johnson and Barbara J. Graves (2010) “ETS-4 is a Transcriptional Regulator of Life Span in Caenorhabditis elegans”. PLoS Genetics, Sept 16;6(9): e1001125.
Amy K. Walker, Fajun Yang, Karen Jiang, Jun-Yuan Ji, Jennifer L. Watts, Aparna Purushotham, Olivier Boss, Michael L. Hirsch, Scott Ribich, Jesse J. Smith, Kristine Israelian, Christoph H. Westphal, Joseph T. Rodgers, Toshi Shioda, Sarah Elson, Peter Mulligan, Hani Najafi-Shoushtari, Josh C. Black, Jitendra K. Thakur, Lisa C. Kadyk, Jonathan Whetstine, Raul Mostoslavsky, Pere Puigserver, Xiaoling, Li, Nicholas J. Dyson, Anne C. Hart, and Anders M. Naar (2010) “Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP”. Genes and Development 24: 1403-1417.
Bin Liang, Kim Ferguson, Lisa Kadyk, and Jennifer L. Watts (2010) “The role of nuclear receptor NHR-64 in fat storage regulation in Caenorhabditis elegans”. PLoS One 5(3) e9869.
Kyleann K. Brooks, Bin Liang, Jennifer L. Watts (2009) “The Influence of Bacterial Diet on Fat Storage in C. elegans” PLoS One 4(10) e7545.
Jennifer L. Watts (2009) “Fat Synthesis and Adiposity Regulation in Caenorhabditis elegans” Trends in Endocrinology and Metabolism 20: 58-65. Review.
Jennifer L. Watts (2008) “Fattening Up without Overeating” Cell Metabolism 8: 95-96. Preview.
Trisha J. Brock, John Browse and Jennifer L. Watts (2007) “Fatty Acid Desaturation and the Regulation of Adiposity in Caenorhabditis elegans.” Genetics 176: 865-875.
Lena K. Schroeder, Susan Kremer, Maxwell J. Kramer, Erin Currie, Elizabeth Kwan, Jennifer L. Watts, Andrea L. Lawrenson and Greg Hermann (2007) “Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelle”. Mol Biol Cell 18: 995- 1008.
*Homare M. Kubagawa, Jennifer L. Watts, Chad Corrigan, Johnathan W. Edmonds, Elizabeth Sztul, John Browse, and Michael A. Miller (2006) “Oocyte signals derived from polyunsaturated fatty acids control sperm recruitment in vivo. Nature Cell Biology 8: 1143-1148.
Fajun Yang, Bryan W. Vought, John S. Satterlee, Z.-Y. Jim Sun, Jennifer L. Watts, Rosalie DeBeaumont, R. Mako Saito, Sven G. Hyberts, Shaosong Yang, Christine Macol, Lakshmanan Iyer, Robert Tjian, Sander van den Heuvel, Anne Hart, Gerhard Wagner, and Anders M. Näär (2006) “An ARC/ Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.” Nature 442: 700-704.
Trisha J. Brock, John Browse, and Jennifer L. Watts (2006) “Genetic Regulation of Unsaturated Fatty Acid Composition in C. elegans.” PLoS Genetics 2 e108.
Jennifer L. Watts and John Browse (2006) “Dietary manipulation implicates lipid signaling in the maintenance of C. elegans germ cells” Developmental Biology 292: 381-392.
Amanda H. Kahn-Kirby, J.L.M Dantzker, John Browse, Cornelia I. Bargmann, and Jennifer L Watts (2004) “Specific polyunsaturated fatty acids drive TRPV-dependent sensory signaling in vivo. Cell 119: 889-900.
Kaveh Ashrafi, Francesca Y. Chang, Jennifer L. Watts, Andrew G. Fraser, Ravi S. Kamath, Julie Ahringer, and Gary Ruvkun (2003) “Genome-wide RNAi analysis of C. elegans fat regulatory genes” Nature 421: 268-272.
Jennifer L. Watts, Eric Phillips, Katharine R. Griffing, and John Browse (2003) “Deficiencies in C20 polyunsaturated fatty acids cause behavioral and developmental defects in C. elegans fat-3 mutants” Genetics 163: 581-589.
Marina Kniazeva, Matt Sieber, Scott McCauley, Kang Zhang, Jennifer L. Watts, and Min Han. “Suppression of the ELO-2 FA elongation activity results in alterations of the fatty acid composition and multiple physiological defects, including abnormal ultradian rhythms, in C. elegans” Genetics 163 (2003) 159-160.
Jennifer L. Watts and John Browse. “Genetic dissection of polyunsaturated fatty acid synthesis in Caenorhabditis elegans” Proc. Nat. Acad. Sci. USA 99 (2002) 5854-5859.
James G. Wallis, Jennifer L. Watts, and John Browse. (2002) “Polyunsaturated fatty acid synthesis. What will they think of next?” Trends Biochem Sci. 27 467-473 Review.
Jennifer L. Watts and John Browse. “A Palmitoyl-CoA-Specific Delta 9 Fatty Acid Desaturase from Caenorhabditis elegans” Biochem. Biophys. Res. Comm. 272 (2000) 263-269.
Marlyse Peyou-Ndi, Jennifer L. Watts, John Browse. “Identification and Characterization of an Animal Delta-12 Fatty Acid Desaturase from Caenorhabditis elegans” Archives of Biochemistry and Biophysics 376 (2000) 399-408.
Jennifer L. Watts and John Browse. “Isolation and Characterization of a Delta-Fatty Acid Desaturase from Caenorhabditis elegans” Archives of Biochemistry and Biophysics 362 (1999) 175-182.