In collaboration with the Telese and Benner labs at UC San Diego we used csRNA-seq to capture changes in brain gene expression in rats with addiction-like behavior and control which identified transcription factor-centered regulatory mechanisms implicated in addiction, including those regulated by glucocorticoid receptors in glial cells. And even cooler, no rats had to die for these experiments as csRNA-seq made is possible to capture the complete transcriptome including unstable enhancer RNAs from banked tissues! (Link to paper: doi: 10.3389/fnins.2022.858427)