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Research

Microfluidic device for particle separation with Airfoil shaped pillars

Deterministic Lateral Displacement (DLD) for nanoparticle separation: DLD is a continuous microfluidic separation device that uses a repeating array of pillars to selectively displace particles having a mean diameter greater than the critical diameter. The critical diameter is an emergent property influenced by pillar shape, size, and spacing in addition to the suspending fluid and target particle properties. This project will design and fabricate microfluidic device for DLD demonstration using conventional soft lithography technique. (Supported by WSU New Faculty Seed grant-131078, Collaboration with Analog Devices, Inc.)

  • B. M. Dincau,  A. Aghilinejad, X. Chen, SY Moon, and J.-H. Kim*, “Vortex-free high-Reynolds deterministic lateral displacement (DLD) via airfoil pillars“, Microfluidics and Nanofluidics, Microfluidics and Nanofluidics, 2018, 22, 137.
  • B. M. Dincau,  A. Aghilinejad, T. Hammersley,  X. Chen, and J.-H. Kim*, “Deterministic lateral displacement (DLD) in the high Reynolds number regime-high throughput and dynamic separation characteristics”, Microfluidics and Nanofluidics, 2018, 22 (6), 59
  • B. Dincau, A. Aghilinejad, X. Chen, and J.-H. Kim, “Characterizaing the turbulent regime for deterministic lateral displacement (DLD) devices”, ASME IMECE 2017-71892, November 3-9, 2017.

Novel printing technology with nano-ink

Novel printing technology with nanoink for biosensor fabrication: Develop a novel non-contact printing method for nanomaterials and biomolecules using capillary nanoink bridge. (Supported by DoD CDMRP W81XWH-17-1-0083)

  • S.-J. Kahng, C. Cerwyn, B. M. Dincau, J.-H. Kim, I. V. Novosselov, M. P. Anantram, and J.-H. Chung, “Nanoink Bridge-induced Capillary Pen Printing for Checmial and Biological Sensors”, Nanotechnology, 2018, 29, 335304

Micro/nanoneedle fabrication for biomedical applications

Design and develop micro/nanostructured needle fabrication for biomedical application. (Supported by WSU Vancouver mini grant and Probus Med Tech Inc.)

  • B. M. Dincau, Y. Lee, J.-H. Kim* and W.-H. Yeo,  “Recent advances in nanoparticle concentration and viral detection by using biosensors and bioelectronics”, Sensors 2017, 17(10), 2316
  • S.J. Kahng, H.-B. Lee, J.-H. Chung, and J.-H. Kim*, “Nanostructured Tip-Shaped Biosensors: Application of Six Sigma Approach for Enhanced Manufacturing”, Sensors 2017, 17(1), 17 (invited paper)
  • D. Saadat-Moghaddam and J.-H. Kim*, “A Microneedle Functionalized with Polyethyleneimine and Nanotubes for Highly Sensitive, Label-Free Quantification of DNA”, Sensors, 2017, 17(8), 1883
  • S.J. Kahng, H.-B. Lee, J.-H. Chung, and J.-H. Kim*, “Dendritic nanotip: Controlled fabrication and amplification-free detection of DNA”, Sensors (invited paper), 2016

Study of flow-boiling morphological characteristics with surface wettability gradient in microchannel flow

In this study, we investigate two-dimensional flow-boiling morphological characteristics with hydrophilic coating on a hot-spot. (Supported by NSF CBET-1707056 and Undergraduate Summer Research program)

  • Y. Hayashi, N. Saneie, G. Yip, Y. Kim*, and J.-H. Kim, “Metallic Nanoemulsion with Galinstan for High Heat-Flux Thermal Management”, accepted to International Journal of Heat and Mass Transfer, 2016

Soft nanocomposite for wearable electronics

Synthesis of soft nanocomposite for flexible, wearable bioelectronics: Develop a flexible, wearable bioelectronic system using an elastomeric hybrid nanocomposite, composed of zero-dimensional carbon nanoparticles and one-dimensional carbon nanotubes. A fast and facile fabrication route is used to construct a unique architecture by microscale replica molding process using an ultra-soft elastomeric membrane in conjunction with the nanomaterials. (Supported by Undergraduate Summer Research program and New Faculty Startup)

  • F. Fondjo and J.-H. Kim, “Hybrid nanocomposite membrane for wearable electronics”, ASME IMECE 2017- , November 3-9, 2017.
  • F. Fondjo, M Teller, C. Howe, W.-H. Yeo, and J.-H. Kim, “Synthesis of a Soft Nanocomposite for Flexible, Wearable Bioelectronics”, IEEE Electronic Components and Technology Conference 2017, May 30 – June 2, 2017, Orlando, FL.

Development of Point-of-Care diagnosis for low-resource settings

  • G. Fotouhi, A. Cairns, J.-H. Kim, K. Olson, K.-H. Lee, and J.-H. Chung, “Study of heat-cured polyethyleneimine coated on a microtip for qPCR analysis”, in preparation, 2016
  • S. Inoue, H.-B. Lee, A. L. Becker, K. M. Weigel, J.-H. Kim, K.-H. Lee, G. A. Cangelosi, and J.-H. Chung, “Dielectrophoretic characterization of antibiotic-treated Mycobacterium tuberculosis complex cells”, Analytical Bioanalytical Chemistry, 407(25) 7673-7680, 2015
  • M. Hiraiwa, J.-H. Kim*, H.-B. Lee, S. Inoue, A. L. Becker, K. Weigel, G. A. Cangelosi, K.-H. Lee, and J.-H. Chung, “Amperometric immunosensor for rapid detection of Mycobacterium tuberculosis”, Journal of Microemechanics and Microengineering. 25 055013, 2015

Biomolecule (DNA, proteins, bacteria, and viruses) manipulation for single molecule analysis

A wafer-scale nanofluidic system that incorporates an array of accessible open nanochannels and nano-microtrappers to enrich and elongate target molecules (DNA) via the combination of an electric field and hydrodynamic force. (Supported by New Faculty Startup)

  • Y.-S. Kim, B. M. Dincau, Y.-T. Kwon, W.-H. Yeo, and J.-H. Kim*, “Directly Accessible and Transferrable Nanofluidic Systems for Biomolecule Manipulation”, ACS sensors, 2019, Under review