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John Clarke Lab Xenobiotic Exposures and Toxicities

Scientific mission

Toxicities from xenobiotic exposures are a significant burden on human health. These exposures occur both intentionally (drugs and dietary supplements) and unintentionally (environmental contamination and naturally occurring toxins). Our focus is on the metabolism and disposition of xenobiotics as key factors in determining toxicity, and our goal is provide quantifiable endpoints that can be used to identify at-risk populations.

Sources of xenobiotic exposures

Pharmaceuticals
Dietary Supplements
Environmental Contamination
Natural Sources

 

 

 

 

 

 

 

 

 

Satellite image of Lake Erie blue-green algal bloom (2011)