Publications

Research, Review, and Book Chapters

• Giassetti MI, Miao D, Law NC, Oatley MJ, Park J, Robinson LD, Maddison LA, Bernhardt ML, Oatley JM.ARRDC5 expression is conserved in mammalian testes and required for normal sperm morphogenesis. Nat Commun. 2023 Apr 17;14(1):2111. doi: 10.1038/s41467-023-37735-y. PubMed PMID: 37069147; PubMed Central PMCID: PMC10110545.

• Law NC. Lineage Tracing of Spermatogonial Stem Cells Within the Male Germline. Methods Mol Biol.2023;2656:309-324. doi: 10.1007/978-1-0716-3139-3_16. PubMed PMID: 37249878.

• Lord T, Law NC, Oatley MJ, Miao D, Du G, Oatley JM. A novel high throughput screen to identify candidate molecular networks that regulate spermatogenic stem cell functions†. Biol Reprod. 2022 Jun 13;106(6):1175-1190. doi: 10.1093/biolre/ioac048. PubMed PMID: 35244684; PubMed Central PMCID: PMC9198950.

• Gewiss RL, Law NC, Helsel AR, Shelden EA, Griswold MD. Two distinct Sertoli cell states are regulated via germ cell crosstalk†. Biol Reprod. 2021 Dec 20;105(6):1591-1602. doi: 10.1093/biolre/ioab160. PubMed PMID: 34494084; PubMed Central PMCID: PMC8689118.

• Zhao L, Law NC, Gomez NA, Son J, Gao Y, Liu X, de Avila JM, Zhu MJ, Du M. Obesity Impairs Embryonic Myogenesis by Enhancing BMP Signaling within the Dermomyotome. Adv Sci (Weinh). 2021 Nov;8(22):e2102157. doi: 10.1002/advs.202102157. Epub 2021 Oct 14. PubMed PMID: 34647690; PubMed Central PMCID: PMC8596142.

• Du G, Oatley MJ, Law NC, Robbins C, Wu X, Oatley JM. Proper timing of a quiescence period in precursor prospermatogonia is required for stem cell pool establishment in the male germline. Development. 2021 May 1;148(9). doi: 10.1242/dev.194571. Epub 2021 Apr 30. PubMed PMID: 33929507; PubMed Central PMCID: PMC8126406.

• Law NC, Oatley JM. Developmental underpinnings of spermatogonial stem cell establishment. Andrology.2020 Jul;8(4):852-861. doi: 10.1111/andr.12810. Epub 2020 May 24. Review. PubMed PMID: 32356598; PubMed Central PMCID: PMC8324036.

• Law NC, Oatley MJ, Oatley JM. Developmental kinetics and transcriptome dynamics of stem cell specification in the spermatogenic lineage. Nat Commun. 2019 Jun 26;10(1):2787. doi: 10.1038/s41467-019-10596-0. PubMed PMID: 31243281; PubMed Central PMCID: PMC6594958.

• Hermann BP, Cheng K, Singh A, Roa-De La Cruz L, Mutoji KN, Chen IC, Gildersleeve H, Lehle JD, Mayo M, Westernströer B, Law NC, Oatley MJ, Velte EK, Niedenberger BA, Fritze D, Silber S, Geyer CB, Oatley JM, McCarrey JR. The Mammalian Spermatogenesis Single-Cell Transcriptome, from Spermatogonial Stem Cells to Spermatids. Cell Rep. 2018 Nov 6;25(6):1650-1667.e8. doi: 10.1016/j.celrep.2018.10.026. PubMed PMID: 30404016; PubMed Central PMCID: PMC6384825.

• Law NC, Oatley JM. Spermatogonial Stem Cell and Niche. In: Skinner MK, editor. Encyclopedia of Reproduction 2nd Edition ed. San Diego, United States: Elsevier Inc.; 2018. Chapter Volume 1; p.117-123. 3868p.

• Law NC, Donaubauer EM, Zeleznik AJ, Hunzicker-Dunn M. How Protein Kinase A Activates Canonical Tyrosine Kinase Signaling Pathways To Promote Granulosa Cell Differentiation. Endocrinology. 2017 Jul 1;158(7):2043-2051. doi: 10.1210/en.2017-00163. PubMed PMID: 28460125; PubMed Central PMCID: PMC5505220.

• Law NC, White MF, Hunzicker-Dunn ME. G protein-coupled receptors (GPCRs) That Signal via Protein Kinase A (PKA) Cross-talk at Insulin Receptor Substrate 1 (IRS1) to Activate the phosphatidylinositol 3-kinase (PI3K)/AKT Pathway. J Biol Chem. 2016 Dec 30;291(53):27160-27169. doi: 10.1074/jbc.M116.763235. Epub 2016 Nov 17. PubMed PMID: 27856640; PubMed Central PMCID: PMC5207145.

• Herndon MK, Law NC, Donaubauer EM, Kyriss B, Hunzicker-Dunn M. Forkhead box O member FOXO1 regulates the majority of follicle-stimulating hormone responsive genes in ovarian granulosa cells. Mol Cell Endocrinol. 2016 Oct 15;434:116-26. doi: 10.1016/j.mce.2016.06.020. Epub 2016 Jun 17. PubMed PMID: 27328024; PubMed Central PMCID: PMC4983523.

• Donaubauer EM, Law NC, Hunzicker-Dunn ME. Follicle-Stimulating Hormone (FSH)-dependent Regulation of Extracellular Regulated Kinase (ERK) Phosphorylation by the Mitogen-activated Protein (MAP) Kinase Phosphatase MKP3. J Biol Chem. 2016 Sep 9;291(37):19701-12. doi: 10.1074/jbc.M116.733972. Epub 2016 Jul 15. PubMed PMID: 27422819; PubMed Central PMCID: PMC5016702.

• Puri P, Little-Ihrig L, Chandran U, Law NC, Hunzicker-Dunn M, Zeleznik AJ. Protein Kinase A: A Master Kinase of Granulosa Cell Differentiation. Sci Rep. 2016 Jun 21;6:28132. doi: 10.1038/srep28132. PubMed PMID: 27324437; PubMed Central PMCID: PMC4914995.

• Law NC, Hunzicker-Dunn ME. Insulin Receptor Substrate 1, the Hub Linking Follicle-stimulating Hormone to Phosphatidylinositol 3-Kinase Activation. J Biol Chem. 2016 Feb 26;291(9):4547-60. doi: 10.1074/jbc.M115.698761. Epub 2015 Dec 23. PubMed PMID: 26702053; PubMed Central PMCID: PMC4813480.

• Law NC, Weck J, Kyriss B, Nilson JH, Hunzicker-Dunn M. Lhcgr expression in granulosa cells: roles for PKA-phosphorylated β-catenin, TCF3, and FOXO1. Mol Endocrinol. 2013 Aug;27(8):1295-310. doi: 10.1210/me.2013-1025. Epub 2013 Jun 10. PubMed PMID: 23754802; PubMed Central PMCID: PMC3725343.

• Hunzicker-Dunn ME, Lopez-Biladeau B, Law NC, Fiedler SE, Carr DW, Maizels ET. PKA and GAB2 play central roles in the FSH signaling pathway to PI3K and AKT in ovarian granulosa cells. Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):E2979-88. doi: 10.1073/pnas.1205661109. Epub 2012 Oct 8. PubMed PMID: 23045700; PubMed Central PMCID: PMC3497822.