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Washington State University W. M. Keck Biomedical Materials Research Lab

Plasma sprayed calcium phosphate coated implants for bone regeneration

Plasma spray is a versatile surface modification technique utilized to improve bioactivity and osteoconductivity of implants for orthopaedic and dental applications. Hydroxyapatite is commonly used as a bioceramic coating material, and can be used as the base for localized dopant and drug delivery. Dopants within the coating and drugs loaded post coating, can further enhance osteoconductivity, osteoinductivity, antibacterial efficacy, and other beneficial therapeutics. Our work demonstrates optimized plasma spray and coating material modifications for improved bone healing. We have also reported combination of additive manufacturing and plasma spray techniques to improve crystallinity and interfacial strength.

Selected publications

  • Roy, M., Bandyopadhyay, A. and Bose, S., Surface and Coatings Technology, 205, p. 2785-92 (2011).
  • Fielding, G.A., Roy, M., Bandyopadhyay, A. and Bose, S., Acta Biomater., 8, p.3144-52 (2012).
  • S Bose, D Ke, A Vu, A Bandyopadhyay, S Goodman, ACS Applied Mater. & Interfaces, 12, 33465-472 (2020).
  • S Bose, S Vahabzadeh, D Banerjee, D Ke,, Materials Today Comm, 21, 100534, (2019).
  • Vu, A.A., Robertson, S.F., Ke, D., Bandyopadhyay, A., Bose, S., Acta Biomater., 92, p.325-35 (2019).