Selected Recent Publications

  1. Chae S. A., J. S. Son, J. M. de Avila, M. Du, and M. J. Zhu. (2022). Maternal exercise improves epithelial development of fetal intestine by enhancing apelin signaling and oxidative metabolism. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, In press. (IF: 3.619) 
  2. Liu, X., L. Zhao, Y. Chen, J.S. Son, S. A. Chae, Q. Tian, Y. Gao, J. M. de Avila, M. J. Zhu, and M. Du. (2022). AMP-activated protein kinase inhibition in fibro-adipogenic progenitors impairs muscle regeneration and increases fibrosis. Journal of Cachexia, Sarcopenia and Muscle. In press (IF: 12.063)
  3. Chae, S. A., J. S. Son, L. Zhao, Y. Gao, X. Liu, J. M. de Avila, M. J. Zhu, and M. Du. (2022). Exerkine apelin reverses obesity-induced placental dysfunction by accelerating mitochondrial biogenesis in mice. American Journal of Physiology-Endocrinology and Metabolism. 322: E467-479. (IF: 5.382)
  4. Liu, X., L. Zhao, Y. Chen, Y. Gao, Q. Tian, J. Sun, S. Chae, J. de avila, M. J. Zhu, and M. Du. (2022). Obesity induces adipose fibrosis and collagen cross-linking through suppressing AMPK and enhancing lysyl oxidase expression. BBA-Molecular Basis of Disease. 1868: 166454.
  5. Gao, Y., L. Zhao, J.S. Son, X. Liu, Y. Chen, M. J. Deavilla, M. J. Zhu, G. Murdoch, and M. Du. (2022). Maternal exercise before and during pregnancy facilitates embryonic myogenesis by enhancing thyroid hormone signaling. Thyroid. 32: 581-593.
  6. Yu X., Y. Ma, Y. Luo, G. Tang, Z. Jiang, J. Zhang, B. Ye, Z. Huang, Y. Luo, M. Du, and B. Wang. (2022).  Neonatal vitamin A administration increases intramuscular fat by promoting angiogenesis and preadipocyte formation. Meat Science. 191: 108847.
  7. Zhang Y., Y. Guo, Y. Luo, M. Du, X. Yin, X. Xu, and G. Zhang. (2022). Integrated metabolomics and transcriptome revealed the effect of fermented Lycium barbarum reside promoting Ovis aries immunity. Frontiers in Immunology. 13: 889436.
  8. Son J.S., SA Chae, L. Zhao, H. Wang, J. M. de Avila, M. J. Zhu, Z. Jiang, and M. Du. (2022). Maternal exercise intergenerationally derives muscle-based thermogenesis via activation of apelin-AMPK signaling. EBioMedicine. 76: 103842.
  9. Chae, S. A., J. S. Son, and M. Du. (2022). Prenatal exercise in fetal development: a placental perspective. FEBS Journal. 289: 3058–3071.
  10. Wang, H.N., J. Z. Xiang, Z. Qi, and M. Du. (2022). Plant extracts in prevention of obesity. Critical Reviews in Food Science and Nutrition. 62: 2221-2234.
  11. Chen, Y.T., Q.Y. Yang, Y. Hu, X.D. Liu, J.M. de Avila, M.J. Zhu, P.W. Nathanielsz, and M. Du. (2021).  Imprinted LncRNA Dio3os preprograms intergenerational brown fat thermogenesis and obese resistance. Nature Communications. 12, 6845.
  12. Zhao, L., N. C. Law, N. A. Gomez, J. Son, Y. Gao, J. M. de Avila, M. J. Zhu, and M. Du. (2021). Obesity impairs embryonic myogenesis by enhancing BMP signaling within the dermomyotome. Advanced Science. 8: 2102157.
  13. Chen, Y., G. Ma, Y. Hu, Q. Yang, J. M. Deavila, M. J. Zhu, and M. Du. (2021). Effects of Maternal Exercise During Pregnancy on Perinatal Growth and Childhood Obesity Outcomes: A Meta-analysis and Meta-regression. Sports Medicine. 51: 2329-2347.
  14. Gu, H.F., F. Ren, X.Y. Mao, and M. Du. (2021). Mineralized and GSH-responsive hyaluronic acid based nano-carriers for potentiating repressive effects of sulforaphane on breast cancer stem cells-like properties. Carbohydrate Polymers. 269: 118294.
  15. Yuan, Q., H. Gong, T. Li, M. Du, and X. Mao. (2021). Supplementation of milk polar lipids to obese dams improves neurodevelopment and cognitive function in male offspring. FASEB Journal. 35: e21454.
  16. Chen, Y. T., Y. Hu, Q. Y. Yang, X. D. Liu, J. S. Son, J. M. de Avila, M. J. Zhu, and M. Du. (2021). Embryonic exposure to hyper glucocorticoids suppresses brown fat development and thermogenesis via REDD1. Science Bulletin. 66: 478-489.
  17. Son, J. S., S. A. Chae, H. Wang, Y. Chen, A. B. Iniguez, J. M. de Avila, M. J. Zhu, and M. Du. (2020). Maternal inactivity programs skeletal muscle dysfunction in offspring mice via attenuating apelin signaling and mitochondrial biogenesis. Cell Reports. 33: 108461.
  18. Liu, X., N. Moffitt-Hemmer, J. Deavilla, A. Li, Q. Tian, A. Bravo-Iniguez, Y. Chen, L. Zhao, M. Zhu, S. Meibergs, J. Busboom, M. Nelson, A. Tibary, and M. Du. (2020). Wagyu-Angus cross improves meat tenderness compared to Angus cattle but unaffected by mild protein restriction during late gestation. Animals. 15: 100144.
  19. Chae, S.A., J.S. Son, M.J. Zhu, J. M. de Avila, and M. Du. (2020). Treadmill running of mouse as a model for studying influence of maternal exercise on offspring. Bio-protocol. 10: e3838.
  20. Zhao, L., J. S. Son, B. Wang, Q .Tian, Y. Chen, X. Liu, J. M. de Avila, M. J. Zhu, and M. Du. (2020). Retinoic acid signaling in fibro/adipogenic progenitors robustly enhances muscle regeneration. EBioMedicine. 60: 103021.
  21. Chen, Y.T., Y. Hu, Q.Y. Wang, J.S. Son, X.D. Liu, J.M. de Avila, M. J. Zhu, and M. Du. (2020). Excessive glucocorticoids during pregnancy impair fetal brown fat development and predisposes offspring to metabolic dysfunctions. Diabetes. 69: 1662-1674.
  22. Tian Q.Y., X.D. Liu, and M. Du. (2020). Alpha-ketoglutarate for adipose tissue rejuvenation. Aging. 12: 13845-13846.
  23. Son, J., L. Zhao, Y. Chen, K. Chen, S. A. Chae, J. M. de Avila, H. Wang, M.J. Zhu, Z. Jiang, and M. Du. (2020). Maternal exercise via exerkine apelin enhances brown adipogenesis and prevents metabolic dysfunction in offspring mice. Science Advances. 6: eaaz0359.
  24. Li, T., H. Gong, Q. Yuan, M. Du, F. Ren, and X. Mao. (2020). Supplementation of polar lipids-enriched milk fat globule membrane in high fat diet fed rats during pregnancy and lactation promotes brown/beige adipocyte development and prevents obesity in male offspring. FASEB Journal. 34: 4619-4634.
  25. Tian, Q., J. Zhao, Q. Yang, B. Wang, J. Deavila, M.J. Zhu, and M. Du. (2020). Dietary alpha-ketoglutarate promotes beige adipogenesis and prevents obesity in middle-aged mice. Aging Cell. 19: e13059.
  26. Zhao, L., B. Wang, N. Gomez, J. Deavila, M. J. Zhu, and M. Du. (2020). Even a Low Dose of Tamoxifen Profoundly Induces Adipose Tissue Browning in Female Mice. International Journal of Obesity. 44,226-234.
  27. Gu, H., X. Mao, and M. Du. (2020). Prevention of breast cancer by dietary polyphenols: role of cancer stem cells. Critical Reviews in Food Science and Nutrition. 60: 810-825.
  28. Zou T., Y. Kang, B. Wang, J. M. Deavilla, J. You, M.J. Zhu, and M. Du. (2019). Raspberry supplementation reduces lipid accumulation and improves insulin sensitivity in skeletal muscle of mice fed a high-fat diet. Journal of Functional Foods. 63: 103572.
  29. Li, X., X. Fu, G. Yang, and M. Du. (2019). Review: Enhancing intramuscular fat development via targeting fibro-adipogenic progenitor cells in meat animals. Animals. 14: 312-321.
  30. Son, J., X. Liu, Q. Tian, L. Zhao, Y. Chen, Y. Hu, S. A. Chae, J. M. Deavila, M. J. Zhu, and M. Du. (2019). Exercise prevents the adverse effects of maternal obesity on placental vascularization and fetal growth. Journal of Physiology. 597: 3333-3347.
  31. Zhao, L., Y. Huang, and M. Du. (2019). Farm Animals for Studying Muscle Development and Metabolism: dual purposes for animal production and human health. Animal Frontiers. 9:3.
  32. Wei, S., A. Li, L. Zhang, and M. Du. (2019). Long noncoding RNAs in adipogenesis and adipose development of meat animals. Journal of Animal Science. 97: 2644-2657.
  33. Wang, H., Y. Chen, X. Mao, and M. Du. (2019). Maternal obesity impairs fetal mitochondriogenesis and brown adipose tissue development partially via upregulation of miR-204-5p. BBA-Molecular Basis of Disease. 1865: 2706-2715.
  34. Wang, H., X. Mao, and M. Du. (2019). Phytanic acid activates PPARa to promote beige adipogenic differentiation of preadipocytes. Journal of Nutritional Biochemistry. 67: 201-211.
  35. Zhao, L., M. Du, J. Gao, B. Zhan, and X. Mao, (2019). Label-free quantitative proteomic analysis of milk fat globule membrane proteins of yak and cow and identification of proteins associated with glucose and lipid metabolism. Food Chemistry. 275: 59-68.
  36. Chen, Y., Y. Yang, and M. Du. (2018). Beyond brown adipogenesis the inheritance of imprinted H19. Non-coding RNA Investigation. 2:64.
  37. Wang, B., C. L. Harris, W. Nie, X. Fu, J. M. Deavila, M. J. Zhu, M. Maquivar, S. M. Parish, J. R. Busboom, M. L. Nelson, and M. Du. (2018). Neonatal vitamin A injection promotes cattle muscle development and increase oxidative muscle fibers. Journal of Animal Science and Biotechnology. 9: 82.
  38. Zhu, M.J., X. Sun, and M. Du. (2018). AMPK in regulation of apical junctions and barrier junction of intestinal epithelium. Tissue Barriers. 6: 1-13.
  39. Harris, C. L., B. Wang, J. M. Deavila, J. R. Busboom, M. Maquivar, S. M. Parish, B. McCann, M. L. Nelson, and M. Du. (2018). Vitamin A administration at birth promotes calf growth and marbling fat development in Angus beef cattle. Journal of Animal Science and Biotechnology. 9: 55.
  40. Ma, Y.N., B. Wang, Z.X. Wang, N. A. Gomez, M. J. Zhu, and M. Du. (2018). Three dimensional spheroid culture of adipose stromal vascular cells for studying adipogenesis in beef cattle. Animals. 12: 2123-2129.
  41. Zhao, L., T. Zou, N. A. Gomez, B. Wang, M. J. Zhu, and M. Du. (2018). Raspberry alleviates obesity-induced inflammation and insulin resistance in skeletal muscle through activation of AMP-activated protein kinase (AMPK) α1. Nutrition & Diabetes. 8: 39.
  42. Zou, T., B. Wang, Q. Yang, J. M. de Avila, M. J. Zhu, J. You, D. Chen, and M. Du. (2018). Raspberry promotes brown and beige adipocyte development in mice fed high-fat diet through activation of AMP-activated protein kinase (AMPK) a1. Journal of Nutritional Biochemistry. 55: 157.
  43. Bibi, S., M. Du, and M. J. Zhu. (2018). Dietary red raspberries reduces colorectal inflammation and carcinogenic risk in DSS-induced colitis in mice. Journal of Nutrition. 51: 40-46.
  44. Zhu, M. J., Kang, Y., Y. Xue, X. Liang, M. P. Gonzalez Carcia, D. Rodgers, D. K. Kagel, and  M. Du. (2018). Red raspberries suppress NLRP3 inflammasome and attenuate metabolic abnormalities in diet-induced obese mice. Journal of Nutritional Biochemistry. 53:96-103.
  45. Xing, T., Y. Kang, X. Xu, B. Wang, M. Du, and M. J. Zhu. (2018). Raspberry supplementation improves insulin signaling and promotes brown-like adipocyte development in white adipose tissue of obese mice. Molecular Nutrition & Food Research. 2018, 62:1701035.
  46. Wang, B., X. Fu, X. Liang, J. M. Deavila, Z. Wang, L. Zhao, Q. Tian, J. Zhao, N. A. Gomez, S. C. Trombetta, M. J. Zhu, and M. Du.(2017). Retinoic acid induces white adipose tissue browning by increasing adipose vascularity and inducing beige adipogenesis of PDGFRa+ adipose progenitors. Cell Discovery. 3:17036.
  47. Sun, X. X. Fu, Q. Y. Yang, M. Du, and M. J. Zhu. (2017). AMPK regulate intestinal differentiation via histone modification of CDX2. Cell Death and Differentiation. 24: 819-831.
  48. Yang, Q., X. Liang, X. Sun, L. Zhang, X. Fu, C. J. Rogers, A. Berim, S. Zhang, S. Wang, B. Wang, M. Foretz, B. Viollet, D. R. Gang, B. D. Rodgers, M. Zhu, and M. Du. (2016). AMPK/α-ketoglutarate axis dynamically mediates DNA demethylation in the Prdm16 promoter and brown adipogenesis. Cell Metabolism. 24: 542-554.

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