Skip to main content Skip to navigation
People

Position:

PhD Student

Education

  • Master of Science in Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), SAS Nagar, India
  • Bachelor of Pharmacy, Delhi Institute of Pharmaceutical Sciences and Research (DIPSAR), University of Delhi, India
  • Diploma of Pharmacy, Delhi Institute of Pharmaceutical Sciences and Research (DIPSAR), University of Delhi, India

Research Interests

  • Enzyme- and transporter-mediated drug disposition
  • In vitroin vivo extrapolation (IVIVE)
  • PBPK modeling for prediction of pharmacokinetics in special populations

About

Aarzoo is a Ph.D. student in the College of Pharmacy and Pharmaceutical Sciences at the Washington State University (WSU), Spokane. She is a pharmacist by profession. During Masters, her project focused on prediction of oral drug absorption using different physiologically based pharmacokinetic (PBPK) modeling software. Thereafter, she worked as a Research Officer at Agency for Science, Technology and Research (A*STAR), Singapore for ~1.5 years. At A*STAR, she was involved in projects on mechanistic prediction of disposition of drugs and environmental toxicants using different in vitro and in silico tools.

Publications:

  1. Thakur A., Tan, Z., Kameyama, T., El-Khateeb, E., Nagpal, S., Malone, S., Jamwal, R. & Nwabufo, C.K. (2021) Bioanalytical strategies in drug discovery and development. Drug metabolism reviews, 53(3): 434-458 (IF 4.5).
  2. Thakur A.#, Pervez M.#, Prasad B, Leeder S., Ontogeny of drug metabolizing enzymes. In: Nagar S., Argikar U., Tweedie D., (Eds.), Enzyme Kinetics in Drug Metabolism: Fundamentals and Applications, (2nd ), 2021, 551-593.
    #Equal contribution
  3. Chapa R., Li C.Y., Basit A., Thakur A., Ladumor M.K., Sharma S., Singh S., Selen A. & Prasad B. (2020) Contribution of uptake and efflux transporters to oral pharmacokinetics of furosemide. ACS Omega, 5(51): 32939-32950 (IF 3.5).
  4. Thakur A.#, Tan S.P.F# & Chan J.C.Y. (2020) Physiologically-based pharmacokinetic modeling for predicting the clinical efficacy of the coadministration of lopinavir and ritonavir against SARS-CoV-2. Clinical Pharmacology & Therapeutics, 108(6):1176-1184 (IF 6.565). #Equal contribution
  5. Ladumor M.K., Thakur A., Sharma S., Rachapally A., Mishra S., Bobe P., Rao K., Pammi P., Kangne H., Levi D., Balhara A., Ghandikota S., Joshi A., Nautiyal V., Prasad B. & Singh S. (2019) An open access repository of protein abundance data of drug metabolizing enzymes and transporters for applications in physiologically based pharmacokinetics (PBPK) modelling and simulation. Scientific Reports-Nature, 9(1):9709 (IF 4.53).
  6. Ladumor M.K., Bhatt D.K., Gaedigk A., Sharma S., Thakur A., Pearce R.E., Leeder J.S., Bolger M.B., Singh S., & Prasad B. (2019) Ontogeny of hepatic sulfotransferases (SULTs) and prediction of age-dependent fractional contribution of sulfation in acetaminophen metabolism. Drug Metabolism and Disposition, 47(8): 818-831 (IF 3.35).

Posters:

  1. Thakur A., Singh D.K., Paine M.F., & Prasad B. Identification of putative novel biomarkers of organic anion transporter 1 and 3 for the prediction of transporter-mediated drug-drug interactions. Presented at ASPET Annual Meeting 2023, St. Louis, Missouri, 18th to 21st May 2023.
  2. Thakur A., Mettu V, Nguyen J.Y., Paine M.F., & Prasad B. Rat as a model for predicting human renal organic anion transporter-mediated drug-drug interactions. Presented at International Society for the Study of Xenobiotics (ISSX) Meeting 2022, Seattle, United States, 11th to 14th September 2022.
  3. Thakur A. & Prasad B. Assessing the effect of organic anion transporter inhibition on circulating pyridoxic acid, an endogenous transporter biomarker, using physiologically-based pharmacokinetic modeling. Presented at ASPET Annual Meeting, EB 2022, Philadelphia, United States, 2nd to 5th April 2022.

Contact:

Telephone: (509) 368-6535

Email: aarzoo.thakur@wsu.edu

LinkedIn

Office Location: Pharmaceutical & Biomedical Sciences Building,  Room# PBS-320, Spokane, WA