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Publications

2023

 

  1. Effect of probenecid on blood levels and renal elimination of furosemide and endogenous compounds in rats: Discovery of putative organic anion transporter biomarkers

  2. Characterization of Gla proteoforms and non-Gla peptides of gamma carboxylated proteins: Application to quantification of prothrombin proteoforms in human plasma

  3. Experimental pharmacology in precision medicine

  4. The Plasma Membrane Monoamine Transporter (PMAT) is Highly Expressed in Neuroblastoma and Functions as an mIBG Transporter

  5. High-Throughput Assay of Cytochrome P450-Dependent Drug Demethylation Reactions and Its Use to Re-Evaluate the Pathways of Ketamine Metabolism

  6. Innovations, Opportunities and Challenges for Predicting Alteration in Drug Metabolizing Enzymes and Transporters Activity in Specific Populations

  7. Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs

  8. Impact of CYP2C:TG Haplotype on CYP2C19 Substrates Clearance In Vivo, Protein Content, and In Vitro Activity

  9. Characterization of Xenobiotic and Steroid Disposition Potential of Human Placental Tissue and Cell Lines (BeWo, JEG-3, JAR, and HTR-8/SVneo) by Quantitative Proteomics

  10. Involvement of the p38/MK2 Pathway in MCLR Hepatotoxicity Revealed through MAPK Pharmacological Inhibition and Phosphoproteomics in HepaRG Cells

  11. Analysis of the interplay of physiological response to food intake and drug properties in food-drug interactions

  12. Identification of endogenous biomarkers of renal organic cation transporters in rats by global metabolomics analysis

  13. High-Resolution Mass Spectrometry Coupled with XCMS Online for High-throughput Detection and Identification of Drug Metabolites

  14. Identification of Putative Novel Biomarkers of Organic Anion Transporter 1 and 3 for the Prediction of Transporter-Mediated Drug-Drug Interactions

  15. Intestinal Metabolism of Diclofenac by Polymorphic UGT2B17 Correlates with its Highly Variable Pharmacokinetics and Safety across Populations

  16. Quantification of Accurate Composition and Total Abundance of Homologous Proteins by Conserved-Plus-Surrogate Peptide Approach: Quantification of UDP Glucuronosyltransferases in Human Tissues

  17. Quantitative Characterization of Clinically Relevant Drug-Metabolizing Enzymes and Transporters in Rat Liver and Intestinal Segments for Applications in PBPK Modeling

  18. Interplay of Breast Cancer Resistance Protein (Bcrp/Abcg2), Sex, and Fed State in Oral Pharmacokinetic Variability of Furosemide in Rats

  19. Dissecting parameters contributing to the underprediction of aldehyde oxidase-mediated metabolic clearance of drugs

  20. Characterization of xenobiotic and steroid disposition potential of human placental tissue and cell lines (BeWo, JEG-3, JAR, and HTR-8/SVneo) by quantitative proteomics

  21. Relevance of Human Aldoketoreductases and Microbial β-Glucuronidases in Testosterone Disposition
  22. An optimized proteomics-based approach to estimate blood contamination and cellular heterogeneity of frozen placental tissue