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Publications

2015

Yin J, Duan H, Shirasaka Y, Prasad B, Wang J. Atenolol Renal Secretion Is Mediated by Human Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Proteins. Drug Metab Dispos2015 Dec;43(12):1872-81doi: 10.1124/dmd.115.066175. Epub 2015 Sep 15. PubMed PMID: 26374172; PubMed Central PMCID: PMC4658496.

Selwyn FP, Cheng SL, Bammler TK, Prasad B, Vrana M, Klaassen C, Cui JY. Developmental Regulation of Drug-Processing Genes in Livers of Germ-Free Mice. Toxicol Sci2015 Sep;147(1):84-103doi: 10.1093/toxsci/kfv110. Epub 2015 Jun 1. PubMed PMID: 26032512; PubMed Central PMCID: PMC4560037.

Chaudhry AS, Prasad B, Shirasaka Y, Fohner A, Finkelstein D, Fan Y, Wang S, Wu G, Aklillu E, Sim SC, Thummel KE, Schuetz EG. The CYP2C19 Intron 2 Branch Point SNP is the Ancestral Polymorphism Contributing to the Poor Metabolizer Phenotype in Livers with CYP2C19*35 and CYP2C19*2 Alleles. Drug Metab Dispos2015 Aug;43(8):1226-35doi: 10.1124/dmd.115.064428. Epub 2015 May 28. PubMed PMID: 26021325; PubMed Central PMCID: PMC4518065.

Liu H, Yu N, Lu S, Ito S, Zhang X, Prasad B, He E, Lu X, Li Y, Wang F, Xu H, An G, Unadkat JD, Kusuhara H, Sugiyama Y, Sahi J. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2- Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration. Drug Metab Dispos2015 Jul;43(7):1008-18doi: 10.1124/dmd.115.064170. Epub 2015 Apr 23. PubMed PMID: 25908246.

Zhang Z, Farooq M, Prasad B, Grepper S, Unadkat JD. Prediction of gestational age-dependent induction of in vivo hepatic CYP3A activity based on HepaRG cells and human hepatocytes. Drug Metab Dispos2015 Jun;43(6):836-42doi: 10.1124/dmd.114.062984. Epub 2015 Mar 23. PubMed PMID: 25802327; PubMed Central PMCID: PMC4429679.

Prasad B, Unadkat JD. The concept of fraction of drug transported (ft ) with special emphasis on BBB efflux of CNS and antiretroviral drugs. Clin Pharmacol Ther2015 Apr;97(4):320-3doi: 10.1002/cpt.72. Epub 2015 Feb 13. PubMed PMID: 25669655.

Wang L, Prasad B, Salphati L, Chu X, Gupta A, Hop CE, Evers R, Unadkat JD. Interspecies variability in expression of hepatobiliary transporters across human, dog, monkey, and rat as determined by quantitative proteomics. Drug Metab Dispos2015 Mar;43(3):367-74doi: 10.1124/dmd.114.061580. Epub 2014 Dec 22. PubMed PMID: 25534768.

Arnold SL, Kent T, Hogarth CA, Schlatt S, Prasad B, Haenisch M, Walsh T, Muller CH, Griswold MD, Amory JK, Isoherranen N. Importance of ALDH1A enzymes in determining human testicular retinoic acid concentrations. J Lipid Res2015 Feb;56(2):342-57doi: 10.1194/jlr.M054718. Epub 2014 Dec 11. PubMed PMID: 25502770; PubMed Central PMCID: PMC4306688.

Kumar V, Prasad B, Patilea G, Gupta A, Salphati L, Evers R, Hop CE, Unadkat JD. Quantitative transporter proteomics by liquid chromatography with tandem mass spectrometry: addressing methodologic issues of plasma membrane isolation and expression-activity relationship. Drug Metab Dispos2015 Feb;43(2):284-8doi: 10.1124/dmd.114.061614. Epub 2014 Dec 8. PubMed PMID: 25488931.