Position:
PhD Student (rotation)
Education
- Master of Science in Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), SAS Nagar, India
- Bachelor of Pharmacy, St. Paul’s College of Pharmacy, Osmania University, Hyderabad, India
Research Interests
- In vitro–in vivo extrapolation (IVIVE) of enzyme-and transporter mediated drug disposition.
- Biomarker aided PBPK modeling for prediction of pharmacokinetics and pharmacodynamics of drugs in specific populations.
About
Gautam is a Ph.D. student in the College of Pharmacy and Pharmaceutical Sciences at the Washington State University (WSU), Spokane. He is a registered pharmacist in Hyderabad, India. During his master’s, he applied the state-of-the-art physiologically based pharmacokinetic (PBPK) modeling for predicting the effect of CYP2D6 enzyme genetic polymorphism on the pharmacokinetics of its substrate drug Propafenone. His subsequent tenure at Dr. Reddy’s Laboratories Limited, Hyderabad, as a biopharmaceutics scientist for ~2 years further honed his expertise. At Dr. Reddy’s, he was involved in projects on mechanistic prediction of the effect of formulation and manufacturing process variables on the bioavailability and bioequivalence of generic drug products using various PBPK modelling software.
Publications:
- Vijaywargi, G., Kollipara, S., Ahmed, T. and Chachad, S., 2023. Predicting transporter mediated drug–drug interactions via static and dynamic physiologically based pharmacokinetic modeling: A comprehensive insight on where we are now and the way forward. Biopharmaceutics & Drug Disposition, 44(3), pp.195-220.
- Boddu, R., Kollipara, S., Vijaywargi, G. and Ahmed, T., 2023. Power of integrating PBPK with PBBM (PBPK-BM): a single model predicting food effect, gender impact, drug-drug interactions and bioequivalence in fasting & fed conditions. Xenobiotica, 53(4), pp.260-278.
Contact:
Telephone: (509) 368-6535
Email: gautam.vijaywargi@wsu.edu
Office Location: Pharmaceutical & Biomedical Sciences Building, Room# PBS-322, Spokane, WA